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New Drug Could Fix Major Issue in Large Dogs

Groundbreaking‌ Drug Could Remove One ​of‍ the Biggest Flaws of ‍Big Dogs

For many dog owners, the advantages and benefits of owning a larger breed canine are apparent.

Bigger dogs generally⁤ make better family pets, especially compared⁤ to smaller breeds, and also make for better ⁣home ⁤security. Bigger dogs are also generally more “dog”-like than some​ of‍ their smaller, ⁣more ‌feline-like counterparts.

But the downside of owning ⁣bigger dogs is also a clear issue: They’re bigger (obviously), making them poor fits for smaller domiciles,⁢ and also eat (and excrete) significantly ⁢more ⁤than ⁣smaller​ dogs. They’re also generally more⁣ prone to health⁢ issues.

Big dogs also just ‍don’t live as long as⁤ smaller dogs — easily the biggest problem for anyone who’s⁤ ever grown particularly ​attached⁢ to ⁢their canine companions.

A Lifespan-Extending Breakthrough

That all being said, a “groundbreaking” new‍ drug from “Loyal,” a San Francisco-based biotech company could be inching closer to ⁣mitigating that last‌ flaw, according the company’s ​CEO ​and founder.

“Today, I’m so proud to announce that Loyal has earned ‍what we believe to be the FDA’s ⁤first-ever formal⁢ acceptance that a drug can be developed and approved to extend lifespan,” CEO Celine Halioua wrote in a Nov.‍ 28 blog post.

She explained: “Four years ago I founded Loyal with ​a simple vision ‌— to bring to market the first drug explicitly ​approved and ⁤labeled for healthy lifespan extension.

“Loyal was ​only a few months old and about five people when we⁣ decided to begin by targeting the‍ abnormally short lifespan of large breed dogs with a drug program we code-named LOY-001.”

She added: “In regulatory parlance, we have completed the technical effectiveness‍ portion‍ of our conditional approval application for LOY-001’s use in large⁣ dog lifespan extension.”

Promising Results ‍and⁢ Expert Opinions

“In my professional ‍opinion, the drug is groundbreaking,” Dr. Ivana Crnec, ⁣a veterinarian with ​the Veterinarians.org foundation, told Fox News.

“We still need to⁣ wait​ and​ see its results and potential side effects, ‌but so far, LOY-001 is definitely promising,” she added to the ​outlet. “The⁤ fact that the FDA described the drug as having ‘reasonable expectations of effectiveness’ says a lot about its potential.”

Dr. Jeffrey Krasnoff, ⁤a​ New York-based veterinarian, ⁢was ‍a ​bit more reserved ⁣in⁣ his excitement for the potential of this life-extending drug.

“It sounds too good to​ be true,” Krasnoff told Fox News.

He added: ‍“I ⁤would love to see the research. It would be awesome if it truly made a difference in ​the ‌longevity⁣ of ‌our large canine friends.”

As to how this⁢ product would work — should it actually hit the markets pending significant ⁣further testing, as ‍Fox ⁢notes —⁢ it’s currently designed as a​ shot to⁣ be administered to one’s dog every ⁤three to six months by their vet.

According to Fox⁣ News, for‍ the development ⁣of this product to‍ continue and‌ hit the public, “a large clinical trial and⁢ a review of safety and manufacturing data” will be required — processes that ⁣will take some ‍time regardless.

Halioua noted in‍ the original blog post that the company is working on developing ⁢a daily pill version of the same product.

A look at the “Loyal” product page shows that the ‌company is primarily selling means to extend a dog’s life.

The product page notes that it expects the various anti-aging drugs ⁢to launch between “Early 2025” ​and “2026.”


The post Groundbreaking Drug Could ⁣Remove One of the⁢ Biggest Flaws of Big Dogs appeared first on The Western Journal.

How have dogs treated with ⁢the drug shown improvements in their overall health and lifespan?

Develops-groundbreaking-lifespan-extending-drug”‍ target=”_blank” rel=”noopener”>Fox ⁢News.

Dr. Crnec ‍also expressed her excitement about the potential impact ⁢of the drug on large breed ​dogs ⁤and their owners. “This drug ‌has the potential to greatly improve the quality of life for these dogs and allow them to live longer, healthier lives,” she ‍said.

According to Loyal, the drug has‌ undergone extensive testing in ‌canine subjects, with promising results. The company⁢ reported that dogs treated‍ with the drug showed significant improvements in overall health and a lengthening of their ‍lifespan.

Implications for Dog Owners

For dog owners ⁣who have previously ​been hesitant⁢ about ⁢owning a larger breed due to their shorter‍ lifespan, this breakthrough drug could be a game-changer. It offers hope that their beloved pets can now enjoy​ a longer, happier life.

Moreover,⁣ this drug⁤ could ⁣also ⁤encourage more adoption of bigger dogs from shelters ​and rescues. Many people are reluctant to adopt larger breeds due to the potential challenges associated with their shorter lifespans. With the availability of a drug that can extend their lifespan, more people‌ may be inclined to give these dogs a loving‍ home.

However, it is important to note that the drug is ⁣still in⁣ the approval process. While the FDA has granted conditional approval for its use in large dog ‌lifespan extension, further studies ‌and testing are ​required to ​ensure its effectiveness and safety in the long term.

Conclusion

The ⁢development of a groundbreaking drug that could extend the lifespan of big dogs is certainly exciting news for dog owners and enthusiasts. If ⁤approved, this drug has the potential to address⁢ one of the biggest flaws associated with ​owning ‌larger breeds and could significantly ⁤improve their overall well-being.

While more research and testing are needed, the promising results so far provide hope that this drug could soon become a ⁤game-changer in the canine world. It ⁤not only offers the possibility‌ of longer and healthier lives for big dogs but also opens doors for the adoption of these wonderful animals by more‍ people.

Indeed, this breakthrough⁢ drug could ⁣be the key to ensuring that big dogs get to‍ enjoy the fullest and longest lives possible, bringing joy and companionship to their owners for many years to ‌come.



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