{"id":2646900,"date":"2026-08-19T10:46:00","date_gmt":"2026-08-19T14:46:00","guid":{"rendered":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/breaking-new-cancer-vaccine-sees-very-exciting-success-in-late-stage-trial\/"},"modified":"2026-08-19T10:55:12","modified_gmt":"2026-08-19T14:55:12","slug":"breaking-new-cancer-vaccine-sees-very-exciting-success-in-late-stage-trial","status":"publish","type":"post","link":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/breaking-new-cancer-vaccine-sees-very-exciting-success-in-late-stage-trial\/","title":{"rendered":"Breaking: New Cancer Vaccine Sees &#8216;Very Exciting&#8217; Success in Late-Stage Trial"},"content":{"rendered":"<aside class=\"mashsb-container mashsb-main mashsb-stretched\"><div class=\"mashsb-box\"><div class=\"mashsb-count mash-medium\" style=\"&quot;\"><div class=\"counts mashsbcount\">22<\/div><span class=\"mashsb-sharetext\">SHARES<\/span><\/div><div class=\"mashsb-buttons\"><a class=\"mashicon-facebook mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fwww.conservativenewsdaily.net%2Fbreaking-news%2Fbreaking-new-cancer-vaccine-sees-very-exciting-success-in-late-stage-trial%2F\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Facebook<\/span><\/a><a class=\"mashicon-twitter mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/twitter.com\/intent\/tweet?text=&amp;url=https:\/\/www.conservativenewsdaily.net\/breaking-news\/?p=2646900&amp;via=ConservNewsDly\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Twitter<\/span><\/a><a class=\"mashicon-subscribe mash-medium mash-nomargin mashsb-noshadow\" href=\"#\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Subscribe<\/span><\/a><div class=\"onoffswitch2 mash-medium mashsb-noshadow\" style=\"display:none\"><\/div><\/div>\n            <\/div>\n                <div style=\"clear:both\"><\/div><\/aside>\n            <!-- Share buttons by mashshare.net - Version: 4.0.47--><p>A recent breakthrough in cancer treatment involves a personalized mRNA-based vaccine developed by Moderna, in collaboration with Merck.The vaccine, called intismeran, has shown promising results in preventing melanoma from returning in patients who have undergone surgery to remove cancerous tissue. When combined with Merck\u2019s immunotherapy drug Keytruda, the vaccine extended the time before cancer recurred and helped prevent its spread, with detailed results expected later this year.<\/p>\n<p>Experts have hailed this as a significant milestone, marking the first prosperous late-stage trial of a personalized mRNA cancer therapy. The advancement signifies a new approach where vaccines are tailored to an individual\u2019s tumor mutations, <a href=\"https:\/\/amzn.to\/3YuVZYV\" >possibly transforming standard cancer treatment<\/a>. The positive trial outcomes have boosted the stock prices of both moderna and Merck, highlighting the commercial and medical potential of this innovative therapy.<\/p>\n<p>The researchers believe this advancement could apply to other types of cancer and represents an exciting step toward expanding personalized medicine. The companies began working on this project in 2016, and the success has been seen as a major breakthrough in immuno-oncology, offering hope for more effective and individualized cancer treatments in the future.  <\/p>\n<p class=\"readmore\">\n    <button onclick=\"showReadMore()\" id=\"readmorebtn\">Read more&#8230;<\/button>\n<\/p>\n<hr id=\"line\">\n<span id=\"more\"><br \/>\n<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\"><br \/>\n<?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><html><body><\/p>\n<section> \t\t\t\t<script>console.log(\"ad slot (AC1)\")<\/script><script>console.log(\"ad slot (IC1)\")<\/script><script>console.log(\"ad slot (IC2)\")<\/script><script>console.log(\"ad slot (IC3)\")<\/script><script>console.log(\"ad slot (IC4)\")<\/script><\/p>\n<p>Two drug companies announced Wednesday that an experimental mRNA-based vaccine has shown promising results in preventing the return of melanoma in patients who have had surgery to remove cancerous tissue.<\/p>\n<p>A late-stage study tested the personalized vaccine intismeran, which was developed by Moderna, in combination with Merck\u2019s cancer immunotherapy drug Keytruda, according to <a href=\"https:\/\/www.wsj.com\/health\/pharma\/moderna-merck-vaccine-succeeds-in-preventing-melanoma-from-returning-540e9e18\" target=\"_blank\" rel=\"noopener\">The Wall Street Journal.<\/a><\/p>\n<p>The companies said the treatment extended the time before cancer returns and helped prevent the cancer from spreading. The companies said details on this results will be released later this year.<\/p>\n<p>\u201cI have a feeling that this is just the beginning of a new field,\u201d Jane Healy, the vice president of oncology at Merck, said.<\/p>\n<p>The results are the first successful late-stage trial for a personalized mRNA cancer treatment.<\/p>\n<p>\u201cI think this is really an important achievement,\u201d Jedd Wolchok, the director of the Meyer Cancer Center at Weill Cornell Medicine and an immunotherapy pioneer, said, according to the website <a href=\"https:\/\/www.statnews.com\/2026\/08\/19\/mrna-cancer-vaccine-trial-melanoma-merck-moderna\/\" target=\"_blank\" rel=\"noopener\">Stat<\/a>.<\/p>\n<p>\u201cIt tells us what might have been considered science fiction 15 or 20 years ago \u2014 that we can produce a personalized vaccine based on sequencing from a tumor from a pathology specimen \u2014 could be used to delay progression of melanoma.<\/p>\n<p>\u201cIt really establishes personalized cancer vaccines as being a new addition to standard cancer therapy.\u201d<\/p>\n<p>\u201cWhile we need to await the final results, this early report is certainly promising and builds on the encouraging results that have been observed across smaller studies over the past decade,\u201d said Catherine Wu, an oncologist at the Dana-Farber Cancer Institute. \u201cIt is highly conceivable that this treatment paradigm will be extendable to other cancers as well.\u201d<\/p>\n<p>Aside from its impact on patients, the results were a shot in the arm for the drug companies, as noted by <a href=\"https:\/\/www.cnbc.com\/2026\/08\/19\/moderna-merck-cancer-vaccine-shows-initial-late-stage-melanoma-data.html\" target=\"_blank\" rel=\"noopener\">CNBC<\/a>.<\/p>\n<p>Merck\u2019s  price rose more than 8 percent while Moderna\u2019s rose about 90 percent. Moderna\u2019s stock soared during the pandemic and crashed afterward, making this treatment its chance to enter the $240-plus-billion cancer-drug market.<\/p>\n<p>\u201cWe are now an oncology company,\u201d Moderna Chief Executive St\u00e9phane Bancel said, according to the Journal. \u201cBy Christmas, you could have a company that\u2019s going back into sales growth for the first time in four years.\u201d<\/p>\n<p>Melanoma patients are \u201cstuck having to deal with the new gravity of that diagnosis and then undergo uncomfortable treatments like surgery, and after that, they\u2019re worried about their cancer coming back,\u201d Merck\u2019s Healy said.<\/p>\n<p>Now, they can have a personalized treatment, she said, noting that because every tumor has a unique array of mutations, the personalized vaccine targets those so that the body\u2019s immune system will attack the cancer, calling the development \u201cvery exciting.\u201d<\/p>\n<p>\u201cWe think [the results are] very meaningful for patients with this disease and really the potential of what it can mean for other patients for cancer in future trials with this particular new class of therapy,\u201d she said.<\/p>\n<p>Healy said the companies have been working on the cancer venture since 2016, according to State.<\/p>\n<p>\u201cIt\u2019s an algorithm as much as it is a therapy,\u201d Healy said.<\/p>\n<p>\u201cI thought the chances that this is going to work are actually pretty small,\u201d Roger Perlmutter, who led Merck\u2019s research team from 2011 to 2020 said last year. \u201cAnd there were a variety of fundamental immunological reasons why I thought that was true, but I thought it was important to be tested.\u201d<\/p>\n<p>\u201cToday\u2019s results represent a landmark moment for adjuvant melanoma treatment,\u201d Professor Georgina Long, the study\u2019s principal investigator and medical director of Melanoma Institute Australia, Chair of Melanoma Medical Oncology and Translational Research at the University of Sydney said, according to a release posted on Merck\u2019s <a href=\"https:\/\/www.merck.com\/news\/merck-and-moderna-announce-phase-3-interpath-001-trial-of-intismeran-autogene-plus-keytruda-met-endpoints-of-recurrence-free-survival-rfs-and-distant-metastasis-free-survival-dmfs-in-patient\/\" target=\"_blank\" rel=\"noopener\">website<\/a>.<\/p>\n<p>\u201cBy intervening earlier in the course of disease, when many cancers are considered most treatable, the goal of adjuvant therapy given after surgery is to increase the possibility of cure for more patients,\u201d Dr. Dean Y. Li, president of Merck Research Laboratories, said.<\/p>\n<div style=\"background-color: #f7f7f7; color: #171717; display: flex;font-size: 16px;font-weight: 600;line-height: 1.5;margin: 24px 0;padding: 18px 20px 18px 30px;text-align: left;\">\n<div style=\"align-self: stretch;border-left: 3px solid #171717;flex-shrink: 0;padding-left: 20px;\"><\/div>\n<p><a style=\"text-decoration: none;\" href=\"https:\/\/www.google.com\/preferences\/source?q=https:\/\/www.westernjournal.com\/\">Choose The Western Journal as your preferred source on Google and never miss reporting that defends truth, protects freedom, and advances Western civilization<\/a><\/div>\n<p style=\"border: 1px solid #f5f5f5; padding: 16px;\">Advertise with The Western Journal and reach millions of highly engaged readers, while supporting our work. <a href=\"https:\/\/www.westernjournal.com\/advertise-us\/?wj_source=article\">Advertise Today<\/a>.<\/p>\n<div style=\"position: relative;\">\n<div class=\"ff-fancy-header-container\"> \t\t\t \t<\/div>\n<div class=\"entry-submit-correction inner-content\">\n<div class=\"correction-form\">\n<form style=\"display: none;\">\n<div class=\"sc-name-field\"> \t\t\t\t\t\t<label>* Name<\/label> \t\t\t\t\t\t<br \/> \t\t\t\t\t\t<input type=\"text\" name=\"name\" required> \t\t\t\t\t<\/div>\n<div class=\"sc--field\"> \t\t\t\t\t\t<label>* <\/label> \t\t\t\t\t\t<br \/> \t\t\t\t\t\t<input type=\"text\" name=\"\" required> \t\t\t\t\t<\/div>\n<p> \t\t\t\t\t<label>* Message<\/label> \t\t\t\t\t<br \/> \t\t\t\t\t<textarea name=\"message\" required><\/textarea> \t\t\t\t\t \t\t\t\t\t<\/p>\n<div class=\"required-message\" style=\"display: none; padding-bottom: 15px;\">* All fields are required.<\/div>\n<p> \t\t\t\t\t<input type=\"submit\" value=\"Submit\" onclick=\"event.preventDefault(); firefly_sc();\"> \t\t\t\t\t \t\t\t\t\t<\/p>\n<div class=\"firefly-sc-confirm\" style=\"display: none;\">Success!<\/div>\n<\/p><\/form>\n<\/p><\/div>\n<\/p><\/div>\n<p> \t\t<script> \t\t\tfunction firefly_sc() { \t\t\t\tif( typeof window.captchaPublicKey == typeof undefined ){ \t\t\t\t\tconsole.error('window.captchaPublicKey is not defined'); \t\t\t\t} \t\t\t\tgrecaptcha.execute( window.captchaPublicKey, { action: 'submit_correction' } ).then( function( token ) { \t\t\t\t\tvar opts = { \t\t\t\t\t\taction:    'firefly_sc_submit', \t\t\t\t\t\tname:      document.querySelector( '.entry-submit-correction [name=\"name\"]' ).value, \t\t\t\t\t\t:     document.querySelector( '.entry-submit-correction [name=\"\"]' ).value, \t\t\t\t\t\tmessage:   document.querySelector( '.entry-submit-correction [name=\"message\"]' ).value, \t\t\t\t\t\tpost_id:   firefly_post_id, \t\t\t\t\t\tcap_token: token \t\t\t\t\t}  \t\t\t\t\tvar inputs = [ 'name', '', 'message' ];  \t\t\t\t\tfor( var i = 0; i < inputs.length; i++ ) if( ! 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The late-stage trial evaluated Moderna\u2019s personalized vaccine, intismeran, combined with Merck\u2019s Keytruda, and results are expected later this year<\/p>\n","protected":false},"author":1,"featured_media":2646901,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mo_disable_npp":"","fifu_image_url":"https:\/\/www.westernjournal.com\/wp-content\/uploads\/2026\/08\/Michael-Featured-Image-1280.jpg","fifu_image_alt":"","footnotes":""},"categories":[33651],"tags":[84374,84375,65128],"class_list":["post-2646900","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-the-western-journal","tag-cancer-vaccine","tag-clinical-trial","tag-medical-breakthrough"],"fifu_image_url":"https:\/\/www.westernjournal.com\/wp-content\/uploads\/2026\/08\/Michael-Featured-Image-1280.jpg","_links":{"self":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2646900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/comments?post=2646900"}],"version-history":[{"count":3,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2646900\/revisions"}],"predecessor-version":[{"id":2646904,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2646900\/revisions\/2646904"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media\/2646901"}],"wp:attachment":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media?parent=2646900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/categories?post=2646900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/tags?post=2646900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}