{"id":2504247,"date":"2025-10-29T09:27:02","date_gmt":"2025-10-29T13:27:02","guid":{"rendered":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/control-arthritis-pain-by-controlling-inflammation\/"},"modified":"2025-10-29T09:28:30","modified_gmt":"2025-10-29T13:28:30","slug":"control-arthritis-pain-by-controlling-inflammation","status":"publish","type":"post","link":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/control-arthritis-pain-by-controlling-inflammation\/","title":{"rendered":"Control Arthritis Pain by Controlling Inflammation"},"content":{"rendered":"<aside class=\"mashsb-container mashsb-main mashsb-stretched\"><div class=\"mashsb-box\"><div class=\"mashsb-count mash-medium\" style=\"&quot;\"><div class=\"counts mashsbcount\">12<\/div><span class=\"mashsb-sharetext\">SHARES<\/span><\/div><div class=\"mashsb-buttons\"><a class=\"mashicon-facebook mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fwww.conservativenewsdaily.net%2Fbreaking-news%2Fcontrol-arthritis-pain-by-controlling-inflammation%2F\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Facebook<\/span><\/a><a class=\"mashicon-twitter mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/twitter.com\/intent\/tweet?text=&amp;url=https:\/\/www.conservativenewsdaily.net\/breaking-news\/?p=2504247&amp;via=ConservNewsDly\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Twitter<\/span><\/a><a class=\"mashicon-subscribe mash-medium mash-nomargin mashsb-noshadow\" href=\"#\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Subscribe<\/span><\/a><div class=\"onoffswitch2 mash-medium mashsb-noshadow\" style=\"display:none\"><\/div><\/div>\n            <\/div>\n                <div style=\"clear:both\"><\/div><\/aside>\n            <!-- Share buttons by mashshare.net - Version: 4.0.47--><p>The article discusses how inflammation is a central factor in the symptoms of COVID-19 and arthritis, including rheumatoid arthritis (RA) and osteoarthritis (OA). It explains that these conditions involve an overactive immune response where cytokines-signaling proteins like TNF-alpha,IL-6,and IL-1 beta-trigger excessive inflammation,leading to pain,swelling,and tissue damage. Shared cellular signaling pathways such as NF-kappaB, MAPK, and JAK\/STAT contribute to this inflammatory process in both COVID-19 and arthritis.<\/p>\n<p>The article highlights Ivermectin, originally an antiparasitic drug, for its potential anti-inflammatory effects by inhibiting these pathways and reducing harmful cytokine activity. It suggests that becuase COVID-19, RA, and OA share similar inflammatory mechanisms, ivermectin might be effective in treating arthritis symptoms as well.<\/p>\n<p>Additionally, the article promotes The wellness Company as a trusted source for american-made Ivermectin, emphasizing affordable pricing and support from medical experts. It concludes by encouraging readers to consider Ivermectin as a means to reduce inflammation and improve joint health, while disclaiming that the details is not medical advice.  <\/p>\n<p class=\"readmore\">\n    <button onclick=\"showReadMore()\" id=\"readmorebtn\">Read more&#8230;<\/button>\n<\/p>\n<hr id=\"line\">\n<span id=\"more\"><\/p>\n<p><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><\/p>\n<section>\n<p><em>(Note: Thank you for supporting businesses like the one presenting a sponsored message below and working with them through the links below, which benefits The Western Journal. We appreciate your support!)<\/em><\/p>\n<h3><strong><u>Inflammation Is at the Core of COVID and Arthritis Symptoms<\/u><\/strong><\/h3>\n<h3>Inflammation is the body&rsquo;s protective response to injury or infection, but sometimes it gets out of control, causing problems in diseases like COVID-19, rheumatoid arthritis (RA), and osteoarthritis (OA). Scientists have discovered that these three <a href=\"https:\/\/amzn.to\/3YuVZYV\" >diseases trigger similar patterns inside<\/a> the body, leading to swelling, pain, and tissue damage.<\/h3>\n<h3>Given Ivermectin&rsquo;s effectiveness against COVID-19, it shouldn&rsquo;t be surprising then that Ivermectin is showing remarkably promising results in treating arthritis.<\/h3>\n<h3><strong><u>COVID and Arthritis<\/u><\/strong><\/h3>\n<h3>When someone has COVID-19, RA, or OA, their <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/cdc-seeks-to-minimize-sepsis-condition-contributing-to-over-700-american-deaths-each-day\/\" title=\"CDC aims to reduce sepsis, a cause of 700+ daily American deaths.\">immune system releases chemicals<\/a> known as cytokines. Cytokines are signaling proteins the body uses to call immune cells to fight infection or heal injury. In these conditions, cytokines become overly active and rally too many immune cells, leading to inflammation that can hurt rather than heal.<\/h3>\n<h3><strong>What Triggers Inflammation? The Inflammatory Cytokine Triad: TNF-<\/strong><strong>&alpha;<\/strong><strong>, IL-6, and IL-1<\/strong><strong>&beta;<\/strong><\/h3>\n<ul>\n<li>\n<h3><strong>Tumor Necrosis Factor-alpha (TNF-<\/strong><strong>&alpha;<\/strong><strong>) is<\/strong>&nbsp;powerful chemical messenger that signals for inflammation. When released in large amounts, it can cause redness, swelling, and pain.<\/h3>\n<\/li>\n<li>\n<h3><strong>Interleukin-6 (IL-6) d<\/strong>irects many immune responses, including fever and the production of protective proteins. Excess IL-6 often results in more inflammation and chronic illness.<\/h3>\n<\/li>\n<li>\n<h3><strong>Interleukin-1 beta (IL-1<\/strong><strong>&beta;<\/strong><strong>), l<\/strong>ike TNF-&alpha; and IL-6, ramps up inflammation and contributes to tissue damage. High levels are common in chronic diseases.<\/h3>\n<\/li>\n<\/ul>\n<h3>This triad appears at elevated levels in COVID-19 (as part of the &ldquo;cytokine storm&rdquo;), RA (causing joint swelling and damage), and OA (resulting in chronic joint pain and breakdown).<\/h3>\n<h3><strong>Arthritis and COVID: Signaling Pathways in Common<\/strong><\/h3>\n<ul>\n<li>\n<h3><strong>NF-<\/strong><strong>&kappa;<\/strong><strong>B (Nuclear Factor kappa-light-chain-enhancer of activated B cells) a<\/strong>cts as a master switch inside cells. Overactivation leads to ongoing inflammation and tissue injury.<\/h3>\n<\/li>\n<li>\n<h3><strong>MAPK (Mitogen-Activated Protein Kinase) is a<\/strong> chain-reaction system, spreading inflammation signals throughout the cell. Branches like p38, ERK1\/2, and JNK amplify cytokine production.<\/h3>\n<\/li>\n<li>\n<h3><strong>JAK\/STAT Pathway is made of p<\/strong>roteins that transmit messages from cytokines like IL-6 into the cell nucleus, triggering more inflammation. JAK inhibitors can block this step to control inflammation in COVID-19 and RA.<\/h3>\n<\/li>\n<\/ul>\n<h3><strong><u>Ivermectin&rsquo;s Anti-Inflammatory Effects<\/u><\/strong><\/h3>\n<h3>Initially developed to kill parasites, studies suggest Ivermectin helps modulate inflammation, as well. How does it do that you might ask:<\/h3>\n<ul>\n<li>\n<h3><strong>NF-<\/strong><strong>&kappa;<\/strong><strong>B Pathway Inhibition b<\/strong>locks the master switch, reducing swelling and tissue damage.<\/h3>\n<\/li>\n<li>\n<h3><strong>Direct Cytokine Suppression l<\/strong>owers TNF-&alpha;, IL-6, and IL-1&beta; levels, limiting harmful inflammation.<\/h3>\n<\/li>\n<li>\n<h3><strong>MAPK Pathway Modulation p<\/strong>revents the inflammatory chain reaction within cells.<\/h3>\n<\/li>\n<li>\n<h3><strong>JAK\/STAT Pathway Interference s<\/strong>lows the JAK\/STAT proteins, putting the brake on chronic inflammation.&nbsp; This is beneficial in COVID-19 and RA.<\/h3>\n<\/li>\n<li>\n<h3><strong>Novel Integrin-Based Mechanism m<\/strong>ay block another &ldquo;doorway&rdquo; that inflammatory messengers use to exacerbate tissue damage.<\/h3>\n<\/li>\n<\/ul>\n<h3>Because COVID-19, RA, and OA  similar internal signaling pathways that drive inflammation, medications like Ivermectin that block these steps could potentially help treat all three.<\/h3>\n<h3><strong><u>Where to Get American Made Ivermectin<\/u><\/strong><\/h3>\n<h3><a href=\"https:\/\/www.twc.health\/products\/ivermectin-capsules?ref=WESTERN\" target=\"_blank\" rel=\"noopener\">For over 30 years, Ivermectin has been trusted worldwide<\/a> &mdash; Nobel Prize&ndash;winning, FDA-approved, and proven safe for millions.<\/h3>\n<h3>We know Ivermectin works, but how can we guarantee that the Ivermectin you order is actually made here in the USA &mdash; not in China? That&rsquo;s where The Wellness Company comes in!<\/h3>\n<h3>The Wellness Company and its <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/could-this-pandemic-hero-be-your-skins-new-best-friend-discover-the-power-of-ivermectin-cream\/\" title=\"Could This Pandemic Hero Be Your Skin\u2019s New Best Friend? Discover the Power of ... Cream\">freedom-fighting medical experts &#038;mdash<\/a>; like Dr. Peter McCullough and Dr. Kelly Victory &mdash; are the gold standard for providing safe, effective, and affordable medical solutions. The Wellness Company&rsquo;s doctors are the doctors who courageously told the truth during the pandemic, and they continue to be the nation&rsquo;s leading voices for putting the health and well-being of the American people above the greed and profits of big pharma and the medical establishment.<\/h3>\n<h3><a href=\"https:\/\/www.twc.health\/products\/ivermectin-capsules?ref=WESTERN\" target=\"_blank\" rel=\"noopener\">The Wellness Company is offering Ivermectin that is 100% made in America!<\/a><\/h3>\n<h3><strong><u>Not Just Made in America &mdash; But at a Price You Can&rsquo;t Beat!<\/u><\/strong><\/h3>\n<h3><a href=\"https:\/\/www.twc.health\/products\/ivermectin-capsules?ref=WESTERN\" target=\"_blank\" rel=\"noopener\">Not only is The Wellness Company offering you Ivermectin made in the USA, it is offering it to you at a price you can&rsquo;t beat!<\/a><\/h3>\n<h3>While most other pharmacies are charging $5 a tablet for Ivermectin, often for lower dosage, The Wellness Company is offering higher dosage Ivermectin (18mg) at just $3.33 a tablet!<\/h3>\n<h3>Discover what life free from inflammation feels like. Start your journey to better joint health today.<\/h3>\n<h3><a href=\"https:\/\/www.twc.health\/products\/ivermectin-capsules?ref=WESTERN\" target=\"_blank\" rel=\"noopener\">Don&rsquo;t wait order a 6-month supply of Ivermectin today!<\/a><\/h3>\n<p><em>Note: The information provided on this website is intended for informational purposes only and should not be considered medical advice or used as a substitute for professional healthcare guidance. It is your responsibility to comply with all applicable laws, regulations, and guidelines regarding the purchase, possession, and use of prescription medications.<\/em><\/p>\n<p><em><strong>Sponsored content is a service paid for by an advertiser and produced by Liftable Media.<\/strong><\/em><\/p>\n<div style=\"position: relative;\">\n<div class=\"ff-fancy-header-container\"> \t\t\t \t<\/div>\n<div class=\"entry-submit-correction inner-content\">\n<div class=\"correction-form\">\n<form style=\"display: none;\">\n<div class=\"sc-name-field\"> \t\t\t\t\t\t<label>* Name<\/label> \t\t\t\t\t\t<br \/> \t\t\t\t\t\t<input type=\"text\" name=\"name\" required> \t\t\t\t\t<\/div>\n<div class=\"sc--field\"> \t\t\t\t\t\t<label>* <\/label> \t\t\t\t\t\t<br \/> \t\t\t\t\t\t<input type=\"text\" name=\"\" required> \t\t\t\t\t<\/div>\n<p> \t\t\t\t\t<label>* Message<\/label> \t\t\t\t\t<br \/> \t\t\t\t\t<textarea name=\"message\" required><\/textarea> \t\t\t\t\t \t\t\t\t\t<\/p>\n<div class=\"required-message\" style=\"display: none; padding-bottom: 15px;\">* All fields are required.<\/div>\n<p> \t\t\t\t\t<input type=\"submit\" value=\"Submit\" onclick=\"event.preventDefault(); firefly_sc();\"> \t\t\t\t\t \t\t\t\t\t<\/p>\n<div class=\"firefly-sc-confirm\" style=\"display: none;\">Success!<\/div>\n<\/p><\/form>\n<\/p><\/div>\n<\/p><\/div>\n<p> \t\t<script> \t\t\tfunction firefly_sc() { \t\t\t\tif( typeof window.captchaPublicKey==typeof undefined ){ \t\t\t\t\tconsole.error('window.captchaPublicKey is not defined'); \t\t\t\t} \t\t\t\tgrecaptcha.execute( window.captchaPublicKey, { action: 'submit_correction' } ).then( function( token ) { \t\t\t\t\tvar opts={ \t\t\t\t\t\taction:    'firefly_sc_submit', \t\t\t\t\t\tname:      document.querySelector( '.entry-submit-correction [name=\"name\"]' ).value, \t\t\t\t\t\t:     document.querySelector( '.entry-submit-correction [name=\"\"]' ).value, \t\t\t\t\t\tmessage:   document.querySelector( '.entry-submit-correction [name=\"message\"]' ).value, \t\t\t\t\t\tpost_id:   firefly_post_id, \t\t\t\t\t\tcap_token: token \t\t\t\t\t}  \t\t\t\t\tvar inputs=[ 'name', '', 'message' ];  \t\t\t\t\tfor( var i=0; i <inputs.length; i++ ) if( ! ( opts[inputs[i]]=document.querySelector( '.entry-submit-correction [name=\"' + inputs[i] + '\"]' ).value ) ) { \t\t\t\t\t\tdocument.querySelector( '.entry-submit-correction .required-message' ).style.display='block'; \t\t\t\t\t\treturn; \t\t\t\t\t}  \t\t\t\t\tdocument.querySelector( '.entry-submit-correction input[type=\"submit\"]' ).style.display='none'; \t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-submitting-img' ).src=firefly_loading_gif_url; \t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-submitting-img' ).style.display='inline-block';  \t\t\t\t\tconsole.log( 'ma subbing' );  \t\t\t\t\tif( firefly_post_id ) opts['post_id']=firefly_post_id;  \t\t\t\t\t\/* Send the data using post with element id name and name2*\/ \t\t\t\t\tvar posting=jQuery.post( firefly_ajax_url, opts );  \t\t\t\t\t\/* Alerts the results *\/ \t\t\t\t\tposting.done( function( response ) { \t\t\t\t\t\tif( response.success ) { \t\t\t\t\t\t\tconsole.log( response.data ); \t\t\t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-submitting-img' ).style.display='none'; \t\t\t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-confirm' ).style.display='block';  \t\t\t\t\t\t\tdataLayer.push( { 'event': 'submit-correction' } ); \t\t\t\t\t\t} \t\t\t\t\t}); \t\t\t\t}); \t\t\t} \t\t<\/script> \t     \t\t\t\t\t\t     \t\t\t\t\t<\/div>\n<p style=\"border: 1px solid #f5f5f5; padding: 16px;\">Advertise with The Western Journal and reach millions of highly engaged readers, while supporting our work. <a href=\"https:\/\/www.westernjournal.com\/advertise-us\/?wj_source=article\">Advertise Today<\/a>.<\/p>\n<div class=\"ff-fancy-header-container\"> \t\t\t \t<\/div>\n<\/section>\n<p><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Note: We appreciate your support of businesses featured in sponsored messages below and encourage you to use the links provided, which help benefit The Western Journal. Thank you!)<\/p>\n<p>Inflammation plays a central role in the symptoms of both COVID-19 and arthritis. While inflammation is the body&#8217;s natural defense against injury or infection, it can become excessive and cause harm in conditions like COVID-19, rheumatoid arthritis (RA), and osteoarthritis (OA). Research shows these diseases trigger similar inflammatory responses that result in swelling, pain, and tissue damage.<\/p>\n<p>Given Ivermectin&#8217;s success in treating COVID-19, it is not surprising that it also shows promising results for arthritis treatment.<\/p>\n<p>In all three conditions-COVID-19, RA, and OA-the immune system releases cytokines, which are proteins that signal immune cells to respond to infection or injury. However, when cytokines are overproduced, they attract too many immune cells causing damaging inflammation instead of healing.<\/p>\n<p>Key inflammatory cytokines involved include:<\/p>\n<p>&#8211; Tumor Necrosis Factor-alpha (TNF-\u03b1): A potent chemical messenger that promotes inflammation leading to redness, swelling, and pain.<br \/>\n&#8211; Interleukin-6 (IL-6): Regulates immune responses such as fever; excess IL-6 contributes to chronic inflammation.<br \/>\n&#8211; Interleukin-1 beta (IL\u20111\u03b2): Increases inflammation and tissue damage; elevated levels are common in chronic diseases.<\/p>\n<p>These cytokines rise significantly during the &#8220;cytokine storm&#8221; seen in severe COVID cases as well as joint swelling and damage seen with RA and OA.<\/p>\n<p>Common cellular pathways driving this inflammation include:<\/p>\n<p>&#8211; NF-kappaB: A master regulator inside cells whose overactivation causes persistent inflammation.<br \/>\n&#8211; MAPK: A signaling cascade amplifying inflammatory signals within cells.<br \/>\n&#8211; JAK\/STAT: Proteins transmitting signals from cytokines like IL\u20116 into cell nuclei; blocking this pathway helps control inflammation.<\/p>\n<p>Ivermectin-originally an antiparasitic drug-also appears to reduce inflammation by:<\/p>\n<p>\u2022 Inhibiting NF-kappaB activity<br \/>\n\u2022 Lowering levels of TNF\u2011\u03b1, IL\u20116, and IL\u20111\u03b2<br \/>\n\u2022 Modulating MAPK signaling<br \/>\n\u2022 Interfering with JAK\/STAT pathways  <\/p>\n<p>Additionally, Ivermectin may block integrin-related mechanisms that worsen tissue damage. Because these inflammatory processes overlap between COVID\u201119 and arthritis types RA\/OA alike,Ivermectin&#8217;s ability to target them suggests potential benefits across these diseases.<\/p>\n<p>For those seeking American-made Ivermectin-which has been FDA-approved for decades-the Wellness Company offers 100% USA-produced medication at competitive prices ($3.33 per 18mg tablet versus $5 elsewhere). Their medical experts advocate for safe alternatives beyond mainstream pharmaceutical interests.<\/p>\n<p>Start your path toward reduced inflammation today by ordering a six-month supply from The Wellness Company!<\/p>\n<p>*Disclaimer: This information is for educational purposes only-not medical advice-and does not replace consultation with healthcare professionals.*<\/p>\n","protected":false},"author":1,"featured_media":2504248,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mo_disable_npp":"","fifu_image_url":"https:\/\/www.westernjournal.com\/wp-content\/uploads\/2025\/10\/Arthritis.jpg","fifu_image_alt":"","footnotes":""},"categories":[33651],"tags":[10240,8450,66083],"class_list":["post-2504247","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-the-western-journal","tag-arthritis","tag-inflammation","tag-pain-management"],"fifu_image_url":"https:\/\/www.westernjournal.com\/wp-content\/uploads\/2025\/10\/Arthritis.jpg","_links":{"self":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2504247","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/comments?post=2504247"}],"version-history":[{"count":3,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2504247\/revisions"}],"predecessor-version":[{"id":2504251,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2504247\/revisions\/2504251"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media\/2504248"}],"wp:attachment":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media?parent=2504247"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/categories?post=2504247"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/tags?post=2504247"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}