{"id":2438895,"date":"2025-05-25T11:59:59","date_gmt":"2025-05-25T15:59:59","guid":{"rendered":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/fda-requires-new-warning-on-common-allergy-drugs-after-severe-new-side-effect-found\/"},"modified":"2025-05-25T12:02:20","modified_gmt":"2025-05-25T16:02:20","slug":"fda-requires-new-warning-on-common-allergy-drugs-after-severe-new-side-effect-found","status":"publish","type":"post","link":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/fda-requires-new-warning-on-common-allergy-drugs-after-severe-new-side-effect-found\/","title":{"rendered":"FDA Requires New Warning on Common Allergy Drugs After Severe New Side Effect Found"},"content":{"rendered":"<aside class=\"mashsb-container mashsb-main mashsb-stretched\"><div class=\"mashsb-box\"><div class=\"mashsb-count mash-medium\" style=\"float:left\"><div class=\"counts mashsbcount\">28<\/div><span class=\"mashsb-sharetext\">SHARES<\/span><\/div><div class=\"mashsb-buttons\"><a class=\"mashicon-facebook mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fwww.conservativenewsdaily.net%2Fbreaking-news%2Ffda-requires-new-warning-on-common-allergy-drugs-after-severe-new-side-effect-found%2F\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Facebook<\/span><\/a><a class=\"mashicon-twitter mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/twitter.com\/intent\/tweet?text=&amp;url=https:\/\/www.conservativenewsdaily.net\/breaking-news\/?p=2438895&amp;via=ConservNewsDly\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Twitter<\/span><\/a><a class=\"mashicon-subscribe mash-medium mash-nomargin mashsb-noshadow\" href=\"#\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Subscribe<\/span><\/a><div class=\"onoffswitch2 mash-medium mashsb-noshadow\" style=\"display:none\"><\/div><\/div>\n            <\/div>\n                <div style=\"clear:both\"><\/div><\/aside>\n            <!-- Share buttons by mashshare.net - Version: 4.0.47--><p>The FDA has issued a warning regarding the use of cetirizine (Zyrtec) and levocetirizine (Xyzal), common allergy medications. This warning states that individuals who stop using these drugs after <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/the-dire-connection-between-diet-and-obesity-depression-and-anxiety\/\" title=\"The Dire Connection Between Diet and Obesity, Depression, and Anxiety\">long-term consumption<\/a> may experience a rare but <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/now-fauci-fires-back-at-nicki-minajs-vaccine-misinformation-no-evidence-vaccine-causes-impotence\/\" title=\"Now Fauci Fires Back At Nicki Minaj\u2019s \u2018Vaccine Misinformation\u2019: \u2018No Evidence\u2019 Vaccine Causes Impotence\">severe side effect<\/a>: intense itching, or pruritus. This itching has been reported in patients who have taken these medications daily for several months or years, and typically did not experience itching before starting the treatment. <\/p>\n<p>The FDA found 209 cases of this side effect,with a significant majority occurring in the U.S. between 2017 and 2023, which is small compared to the over 60 million packages sold. While the exact cause of this reaction is unknown,the FDA is requiring updates to the prescribing information and labels to raise awareness about this potential risk. Patients who experience pruritus upon discontinuation of these medications are encouraged to consult with their healthcare providers and report their experiences to the FDA.  <\/p>\n<p class=\"readmore\">\n    <button onclick=\"showReadMore()\" id=\"readmorebtn\">Read more&#8230;<\/button>\n<\/p>\n<hr id=\"line\">\n<span id=\"more\"><\/p>\n<p><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><?xml encoding=\"utf-8\" ?><\/p>\n<section> \t\t\t\t<script>console.log(\"ad slot (AC1)\")<\/script><script>console.log(\"ad slot (IC1)\")<\/script><script>console.log(\"ad slot (IC2)\")<\/script><script>console.log(\"ad slot (IC3)\")<\/script><script>console.log(\"ad slot (IC4)\")<\/script><\/p>\n<p>The U.S. Food and Drug Administration has issued a warning that people who have used certain common allergy medications may experience a nasty, newfound side effect if they stop prolonged use of the drugs.<\/p>\n<p>In an update titled, &ldquo;<a href=\"https:\/\/www.westernjournal.com\/fda-alters-recall-class-ii-situation\/\" target=\"_blank\" rel=\"noopener\">FDA<\/a> requires warning about rare but severe itching after stopping long-term use of oral allergy medicines cetirizine or levocetirizine,&rdquo; the administration <a href=\"https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-requires-warning-about-rare-severe-itching-after-stopping-long-term-use-oral-allergy-medicines\" target=\"_blank\" rel=\"noopener\">announced<\/a> May 16.<\/p>\n<p>The FDA &ldquo;is warning that patients stopping the oral allergy medicines cetirizine (Zyrtec) or levocetirizine (Xyzal) after long-term use may experience rare but severe itching.&rdquo;<\/p>\n<p>The warning continued: &ldquo;The itching, also called pruritus, has been reported in patients who <a href=\"https:\/\/www.westernjournal.com\/experts-project-long-severe-allergy-season-many-americans\/\" target=\"_blank\" rel=\"noopener\">used these medicines daily<\/a>, typically for at least a few months and often for years.<\/p>\n<p>&ldquo;Patients did not experience itching before starting the medicines.<\/p>\n<p> <script type=\"text\/javascript\"> \t\t\tif ( getCookie( \"ff_subbed\" ) ) { \t\t\t\tdocument.getElementById(\"stnvideo\").remove() \t\t\t} else { \t\t\t\tdocument.addEventListener(\"DOMContentLoaded\", function() { \t\t\t\t\tfunction loadScript(src) { \t\t\t\t\t\tconst script=document.createElement(\"script\"); \t\t\t\t\t\tscript.src=src; \t\t\t\t\t\tscript.async=true; \t\t\t\t\t\tdocument.body.appendChild(script); \t\t\t\t\t} \t\t\t\t\tfunction findPreviousParagraph(selector, x) { \t\t\t\t\t\tconst targetElement=document.querySelector(selector); \t\t\t\t\t\tif (!targetElement) { \t\t\t\t\t\t\tconsole.warn(\"Target element not found.\"); \t\t\t\t\t\t\treturn null; \t\t\t\t\t\t}  \t\t\t\t\t\t\/\/ Get all <\/p>\n<p> elements in order as they appear in the document \t\t\t\t\t\tlet paragraphs=Array.from(document.querySelectorAll(\"p\"));  \t\t\t\t\t\t\/\/ Find the index of the last <\/p>\n<p> before the target element \t\t\t\t\t\tlet targetIndex=paragraphs.findIndex(p=> p.compareDocumentPosition(targetElement) & Node.DOCUMENT_POSITION_PRECEDING);  \t\t\t\t\t\tif (targetIndex===-1 || targetIndex <x) { \t\t\t\t\t\t\tconsole.warn(\"Not enough paragraphs before the target element.\"); \t\t\t\t\t\t\treturn null; \t\t\t\t\t\t}  \t\t\t\t\t\treturn paragraphs[targetIndex - x]; \t\t\t\t\t}  \t\t\t\t\t\/\/ Set up IntersectionObserver \t\t\t\t\tfunction observeElement(element) { \t\t\t\t\t\tif (!element) return;  \t\t\t\t\t\tconst observer=new IntersectionObserver( \t\t\t\t\t\t\t(entries)=> { \t\t\t\t\t\t\t\tentries.forEach(entry=> { \t\t\t\t\t\t\t\t\tif (entry.isIntersecting) { \t\t\t\t\t\t\t\t\t\tconsole.log(\"Paragraph is now visible:\", entry.target.textContent.trim()); \t\t\t\t\t\t\t\t\t\tloadScript(\"https:\/\/embed.sendtonews.com\/player3\/embedcode.js?fk=s28Az7AY\"); \t\t\t\t\t\t\t\t\t\tobserver.disconnect(); \t\t\t\t\t\t\t\t\t} \t\t\t\t\t\t\t\t}); \t\t\t\t\t\t\t}, \t\t\t\t\t\t\t{ threshold: 0.5 } \/\/ Adjust threshold as needed \t\t\t\t\t\t);  \t\t\t\t\t\tobserver.observe(element); \t\t\t\t\t}  \t\t\t\t\t\/\/ Find the 1st paragraph before #stnvideo and observe it \t\t\t\t\tlet paragraphToObserve=findPreviousParagraph(\"#stnvideo\", 2); \t\t\t\t\tobserveElement(paragraphToObserve); \t\t\t\t}); \t\t\t} \t\t<\/script> <\/p>\n<p>&ldquo;Reported cases were rare but sometimes serious, with patients experiencing widespread, severe itching that <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/detransition-awareness-day-event-poised-to-yield-largest-turnout-yet\/\" title=\"\u2018Detransition Awareness Day\u2019 Event Poised To Yield Largest Turnout Yet\">required medical intervention<\/a>.<\/p>\n<p>&ldquo;As a result, we are revising the prescription cetirizine and levocetirizine prescribing information to include a new warning about this risk.<\/p>\n<p>&ldquo;We will subsequently request that manufacturers add a warning about pruritus to the Drug Facts Label of the [over-the-counter] versions.&rdquo;<\/p>\n<p>Due to this <a href=\"https:\/\/www.westernjournal.com\/fda-says-common-allergy-asthma-medication-can-cause-suicidal-thoughts-children\/\" target=\"_blank\" rel=\"noopener\">dangerous new side effect<\/a>, the FDA announced a swift move in the interim.<\/p>\n<p>&ldquo;We are adding a warning about the risk of pruritus after stopping long-term use of prescription cetirizine or levocetirizine to the prescribing information to increase awareness about this rare but serious reaction,&rdquo; the administration noted.<\/p>\n<p>The odds say that most people will not experience the pruritus side effect.<\/p>\n<p>The FDA found 209 cases worldwide of this issue, with 197 being in the United States, between 2017 and 2023.<\/p>\n<p>That total is a fraction of the over 60 million packages sold of the two drugs.<\/p>\n<p>The FDA has yet to figure out the root of the issue.<\/p>\n<p>&ldquo;The underlying mechanism for this risk is unknown, but our evaluation supports a causal relationship between stopping cetirizine or levocetirizine and pruritus,&rdquo; the FDA reported.<\/p>\n<p>&ldquo;Many reports described widespread pruritus that required medical intervention after stopping these medicines, with a <a href=\"https:\/\/amzn.to\/3YuVZYV\" >large number describing significant<\/a> and persistent impact on quality of life and ability to function.<\/p>\n<p>&ldquo;Most patients who experienced pruritus after medicine discontinuation reported using these medicines for more than 3 months; however, some experienced this reaction after less than 1 month of use.<\/p>\n<p>&ldquo;Restarting the medicine resolved pruritus in most individuals, and tapering off the medicine after restarting it resolved symptoms in some who tried this approach.<\/p>\n<p>&ldquo;Other than prolonged use, we have not identified any clear risk factors for pruritus after medicine discontinuation.&rdquo;<\/p>\n<p>If you think you are suffering from the pruritus side effect, the FDA urges either you or your doctor to also notify the FDA MedWatch program, which can be accessed via the FDA website through its &ldquo;<a href=\"https:\/\/www.accessdata.fda.gov\/scripts\/medwatch\/\" target=\"_blank\" rel=\"noopener\">Contact FDA<\/a>&rdquo; tab.<\/p>\n<div style=\"position: relative;\">\n<div class=\"ff-fancy-header-container\"> \t\t\t \t<\/div>\n<div class=\"entry-submit-correction inner-content\">\n<div class=\"correction-form\">\n<form style=\"display: none;\">\n<div class=\"sc-name-field\"> \t\t\t\t\t\t<label>* Name<\/label> \t\t\t\t\t\t<br \/> \t\t\t\t\t\t<input type=\"text\" name=\"name\" required> \t\t\t\t\t<\/div>\n<div class=\"sc--field\"> \t\t\t\t\t\t<label>* <\/label> \t\t\t\t\t\t<br \/> \t\t\t\t\t\t<input type=\"text\" name=\"\" required> \t\t\t\t\t<\/div>\n<p> \t\t\t\t\t<label>* Message<\/label> \t\t\t\t\t<br \/> \t\t\t\t\t<textarea name=\"message\" required><\/textarea> \t\t\t\t\t \t\t\t\t\t<\/p>\n<div class=\"required-message\" style=\"display: none; padding-bottom: 15px;\">* All fields are required.<\/div>\n<p> \t\t\t\t\t<input type=\"submit\" value=\"Submit\" onclick=\"event.preventDefault(); firefly_sc();\"> \t\t\t\t\t \t\t\t\t\t<\/p>\n<div class=\"firefly-sc-confirm\" style=\"display: none;\">Success!<\/div>\n<\/p><\/form>\n<\/p><\/div>\n<\/p><\/div>\n<p> \t\t<script> \t\t\tfunction firefly_sc() { \t\t\t\tif( typeof window.captchaPublicKey==typeof undefined ){ \t\t\t\t\tconsole.error('window.captchaPublicKey is not defined'); \t\t\t\t} \t\t\t\tgrecaptcha.execute( window.captchaPublicKey, { action: 'submit_correction' } ).then( function( token ) { \t\t\t\t\tvar opts={ \t\t\t\t\t\taction:    'firefly_sc_submit', \t\t\t\t\t\tname:      document.querySelector( '.entry-submit-correction [name=\"name\"]' ).value, \t\t\t\t\t\t:     document.querySelector( '.entry-submit-correction [name=\"\"]' ).value, \t\t\t\t\t\tmessage:   document.querySelector( '.entry-submit-correction [name=\"message\"]' ).value, \t\t\t\t\t\tpost_id:   firefly_post_id, \t\t\t\t\t\tcap_token: token \t\t\t\t\t}  \t\t\t\t\tvar inputs=[ 'name', '', 'message' ];  \t\t\t\t\tfor( var i=0; i <inputs.length; i++ ) if( ! ( opts[inputs[i]]=document.querySelector( '.entry-submit-correction [name=\"' + inputs[i] + '\"]' ).value ) ) { \t\t\t\t\t\tdocument.querySelector( '.entry-submit-correction .required-message' ).style.display='block'; \t\t\t\t\t\treturn; \t\t\t\t\t}  \t\t\t\t\tdocument.querySelector( '.entry-submit-correction input[type=\"submit\"]' ).style.display='none'; \t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-submitting-img' ).src=firefly_loading_gif_url; \t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-submitting-img' ).style.display='inline-block';  \t\t\t\t\tconsole.log( 'ma subbing' );  \t\t\t\t\tif( firefly_post_id ) opts['post_id']=firefly_post_id;  \t\t\t\t\t\/* Send the data using post with element id name and name2*\/ \t\t\t\t\tvar posting=jQuery.post( firefly_ajax_url, opts );  \t\t\t\t\t\/* Alerts the results *\/ \t\t\t\t\tposting.done( function( response ) { \t\t\t\t\t\tif( response.success ) { \t\t\t\t\t\t\tconsole.log( response.data ); \t\t\t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-submitting-img' ).style.display='none'; \t\t\t\t\t\t\tdocument.querySelector( '.entry-submit-correction .firefly-sc-confirm' ).style.display='block';  \t\t\t\t\t\t\tdataLayer.push( { 'event': 'submit-correction' } ); \t\t\t\t\t\t} \t\t\t\t\t}); \t\t\t\t}); \t\t\t} \t\t<\/script> \t     \t\t\t\t\t\t     \t\t\t\t\t<\/div>\n<p style=\"border: 1px solid #f5f5f5; padding: 16px;\">Advertise with The Western Journal and reach millions of highly engaged readers, while supporting our work. <a href=\"https:\/\/www.westernjournal.com\/advertise-us\/?wj_source=article\">Advertise Today<\/a>.<\/p>\n<p><script>console.log(\"ad slot (BA1)\")<\/script> \t\t<\/p>\n<div class=\"ff-fancy-header-container\"> \t\t\t \t<\/div>\n<\/section>\n<p><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The U.S. Food and Drug Administration has issued a warning that individuals who have used specific common allergy medications may encounter a severe new side effect if they discontinue long-term use of these drugs. In an update titled, &#8220;FDA requires warning about rare but severe itching after stopping long-term use of oral allergy medicines cetirizine or levocetirizine,&#8221; the agency announced on May 16 that patients ceasing the use of cetirizine (Zyrtec) or levocetirizine (Xyzal) after extended periods may experience rare but intense itching. This condition, known as pruritus, has been reported in those who took these medications daily for several months or even years without prior issues. The FDA noted that cases were uncommon but could be serious, sometimes necessitating medical attention. Consequently, they are updating the prescribing information for these medications to include this new warning and will request manufacturers to add it to over-the-counter versions as well. Although most users are unlikely to experience this side effect-209 cases were identified globally from 2017 to 2023, with 197 occurring in the U.S.-the FDA is still investigating its cause and emphasizes reporting any related symptoms through their MedWatch program<\/p>\n","protected":false},"author":1,"featured_media":2438896,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mo_disable_npp":"","fifu_image_url":"https:\/\/www.westernjournal.com\/wp-content\/uploads\/2025\/05\/Levocetirizine.jpg","fifu_image_alt":"","footnotes":""},"categories":[],"tags":[55891,8468,36377,45708,7267],"class_list":["post-2438895","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","tag-allergy-drugs","tag-fda","tag-health-news","tag-side-effects","tag-warning"],"fifu_image_url":"https:\/\/www.westernjournal.com\/wp-content\/uploads\/2025\/05\/Levocetirizine.jpg","_links":{"self":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2438895","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/comments?post=2438895"}],"version-history":[{"count":3,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2438895\/revisions"}],"predecessor-version":[{"id":2438899,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2438895\/revisions\/2438899"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media\/2438896"}],"wp:attachment":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media?parent=2438895"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/categories?post=2438895"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/tags?post=2438895"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}