{"id":2121152,"date":"2023-12-10T15:28:41","date_gmt":"2023-12-10T20:28:41","guid":{"rendered":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/groundbreaking-drug-could-remove-one-of-the-biggest-flaws-of-big-dogs\/"},"modified":"2023-12-10T15:36:27","modified_gmt":"2023-12-10T20:36:27","slug":"groundbreaking-drug-could-remove-one-of-the-biggest-flaws-of-big-dogs","status":"publish","type":"post","link":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/groundbreaking-drug-could-remove-one-of-the-biggest-flaws-of-big-dogs\/","title":{"rendered":"New Drug Could Fix Major Issue in Large Dogs"},"content":{"rendered":"<aside class=\"mashsb-container mashsb-main mashsb-stretched\"><div class=\"mashsb-box\"><div class=\"mashsb-count mash-medium\" style=\"&quot;\"><div class=\"counts mashsbcount\">18<\/div><span class=\"mashsb-sharetext\">SHARES<\/span><\/div><div class=\"mashsb-buttons\"><a class=\"mashicon-facebook mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fwww.conservativenewsdaily.net%2Fbreaking-news%2Fgroundbreaking-drug-could-remove-one-of-the-biggest-flaws-of-big-dogs%2F\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Facebook<\/span><\/a><a class=\"mashicon-twitter mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/twitter.com\/intent\/tweet?text=&amp;url=https:\/\/www.conservativenewsdaily.net\/breaking-news\/?p=2121152&amp;via=ConservNewsDly\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Twitter<\/span><\/a><a class=\"mashicon-subscribe mash-medium mash-nomargin mashsb-noshadow\" href=\"#\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Subscribe<\/span><\/a><div class=\"onoffswitch2 mash-medium mashsb-noshadow\" style=\"display:none\"><\/div><\/div>\n            <\/div>\n                <div style=\"clear:both\"><\/div><\/aside>\n            <!-- Share buttons by mashshare.net - Version: 4.0.47--><h2>Groundbreaking\u200c Drug Could Remove One \u200bof\u200d the Biggest Flaws of \u200dBig Dogs<\/h2>\n<blockquote>\n<p>For many dog owners, the advantages and benefits of owning a larger breed canine are apparent.<\/p>\n<p>Bigger dogs generally\u2064 make better family pets, especially compared\u2064 to smaller breeds, and also make for better \u2063home \u2064security. Bigger dogs are also generally more \u201cdog\u201d-like than some\u200b of\u200d their smaller, \u2063more \u200cfeline-like counterparts.<\/p>\n<p>But the downside of owning \u2063bigger dogs is also a clear issue: They\u2019re bigger (obviously), making them poor fits for smaller domiciles,\u2062 and also eat (and excrete) significantly \u2062more \u2064than \u2063smaller\u200b dogs. They\u2019re also generally more\u2063 prone to <a href=\"https:\/\/www.westernjournal.com\/mysterious-dog-illness-reported-14-states-leaving-vets-puzzled\/\" target=\"_blank\" rel=\"noopener\">health\u2062 issues<\/a>.<\/p>\n<p>Big dogs also just \u200ddon\u2019t live as long as\u2064 smaller dogs \u2014 easily the biggest problem for anyone who\u2019s\u2064 ever grown particularly \u200battached\u2062 to \u2062their <a href=\"https:\/\/www.westernjournal.com\/couples-dog-survives-mysterious-illness-sweeping-us-say-strangers-suggestion-online-saved\/\" target=\"_blank\" rel=\"noopener\">canine companions<\/a>.<\/p>\n<\/blockquote>\n<h3>A Lifespan-Extending Breakthrough<\/h3>\n<blockquote>\n<p>That all being said, a \u201cgroundbreaking\u201d new\u200d drug from \u201cLoyal,\u201d a San Francisco-based biotech company could be inching closer to \u2063mitigating that last\u200c flaw, according the company\u2019s \u200bCEO \u200band founder.<\/p>\n<p>\u201cToday, I\u2019m so proud to announce that Loyal has earned \u200dwhat we believe to be the <a href=\"https:\/\/www.westernjournal.com\/fda-grants-accelerated-approval-vaccine-life-threatening-mosquito-borne-virus-unheard-us\/\" target=\"_blank\" rel=\"noopener\">FDA\u2019s<\/a> \u2064first-ever formal\u2062 acceptance that a drug can be developed and approved to extend lifespan,\u201d CEO Celine Halioua wrote in a Nov.\u200d 28 <a href=\"https:\/\/loyalfordogs.com\/posts\/loyal-announces-historic-fda-milestone-for-large-dog-lifespan-extension-drug\" target=\"_blank\" rel=\"noopener\">blog post<\/a>.<\/p>\n<p>She explained: \u201cFour years ago I founded Loyal with \u200ba simple vision \u200c\u2014 to bring to market the first drug explicitly \u200bapproved and \u2064labeled for healthy lifespan extension.<\/p>\n<p>\u201cLoyal was \u200bonly a few months old and about five people when we\u2063 decided to begin by targeting the\u200d abnormally short lifespan of large breed dogs with a drug program we code-named LOY-001.\u201d<\/p>\n<p>She added: \u201cIn regulatory parlance, we have completed the technical effectiveness\u200d portion\u200d of our conditional approval application for LOY-001\u2019s use in large\u2063 dog lifespan extension.\u201d<\/p>\n<\/blockquote>\n<h3>Promising Results \u200dand\u2062 Expert Opinions<\/h3>\n<blockquote>\n<p>\u201cIn my professional \u200dopinion, the drug is groundbreaking,\u201d Dr. Ivana Crnec, \u2063a veterinarian with \u200bthe Veterinarians.org foundation, told <a href=\"https:\/\/www.foxnews.com\/health\/anti-aging-drug-dogs-san-francisco-firm-moves-closer-gaining-fda-approval\" target=\"_blank\" rel=\"noopener\">Fox News<\/a>.<\/p>\n<p>\u201cWe still need to\u2063 wait\u200b and\u200b see its results and <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/vaccine-maker-biontech-looking-into-reports-of-heart-inflammation\/\" title=\"Vaccine maker BioNTech looking into reports of heart inflammation\">potential side effects<\/a>, \u200cbut so far, LOY-001 is definitely promising,\u201d she added to the \u200boutlet. \u201cThe\u2064 fact that the FDA described the drug as having \u2018reasonable expectations of effectiveness\u2019 says a lot about its potential.\u201d<\/p>\n<p>Dr. Jeffrey Krasnoff, \u2064a\u200b New York-based veterinarian, \u2062was \u200da \u200bbit more reserved \u2063in\u2063 his excitement for the potential of this life-extending drug.<\/p>\n<p>\u201cIt sounds too good to\u200b be true,\u201d Krasnoff told Fox News.<\/p>\n<p>He added: \u200d\u201cI \u2064would love to see the research. It would be awesome if it truly made a difference in \u200bthe \u200clongevity\u2063 of \u200cour large canine friends.\u201d<\/p>\n<\/blockquote>\n<p>As to how this\u2062 product would work \u2014 should it actually hit the markets pending significant \u2063further testing, as \u200dFox \u2062notes \u2014\u2062 it\u2019s currently designed as a\u200b shot to\u2063 be administered to one\u2019s dog every \u2064three to six months by their vet.<\/p>\n<p>According to Fox\u2063 News, for\u200d the development \u2063of this product to\u200d continue and\u200c hit the public, \u201ca <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/fda-says-one-dose-johnson-johnson-covid-19-vaccine-is-safe-effective\/\" title=\"FDA Says One-Dose Johnson &#038; Johnson COVID-19 Vaccine Is Safe, Effective\">large clinical trial<\/a> and\u2062 a review of safety and manufacturing data\u201d will be required \u2014 processes that \u2063will take some \u200dtime regardless.<\/p>\n<p>Halioua noted in\u200d the original blog post that the company is working on developing \u2062a daily pill version of the same product.<\/p>\n<p>A look at the \u201cLoyal\u201d <a href=\"https:\/\/loyalfordogs.com\/products\" target=\"_blank\" rel=\"noopener\">product page<\/a> shows that the \u200ccompany is primarily selling means to extend a dog\u2019s life.<\/p>\n<p>The product page notes that it expects the various <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/3-promising-anti-aging-drugs-and-an-anti-aging-diet-current-studies\/\" title=\"3 Promising Anti-Aging Drugs and an Anti-Aging Diet: Current Studies\">anti-aging drugs<\/a> \u2062to launch between \u201cEarly 2025\u201d \u200band \u201c2026.\u201d<\/p>\n<hr>\n<p>The post <a rel=\"nofollow\" href=\"https:\/\/www.westernjournal.com\/groundbreaking-drug-remove-one-biggest-flaws-big-dogs\/\">Groundbreaking Drug Could \u2063Remove One of the\u2062 Biggest Flaws of Big Dogs<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/www.westernjournal.com\">The Western Journal<\/a>.<\/p>\n<p> <\/p>\n<h2> How have dogs treated with \u2062the drug shown improvements in their overall health and lifespan?<\/h2>\n<p><span>  Develops-groundbreaking-lifespan-extending-drug&#8221;\u200d target=&#8221;_blank&#8221; rel=&#8221;noopener&#8221;>Fox \u2062News<\/a>.<\/p>\n<p>Dr. Crnec \u200dalso expressed her excitement about the potential impact \u2062of the drug on large breed \u200bdogs \u2064and their owners. \u201cThis drug \u200chas the potential to greatly improve the quality of life for these dogs and allow them to live longer, healthier lives,\u201d she \u200dsaid.<\/p>\n<p>According to Loyal, the drug has\u200c undergone extensive testing in \u200ccanine subjects, with promising results. The company\u2062 reported that dogs treated\u200d with the drug showed significant improvements in overall health and a lengthening of their \u200dlifespan.<\/p>\n<\/blockquote>\n<h3>Implications for Dog Owners<\/h3>\n<blockquote>\n<p>For dog owners \u2063who have previously \u200bbeen hesitant\u2062 about \u2062owning a larger breed due to their shorter\u200d lifespan, this breakthrough drug could be a game-changer. It offers hope that their beloved pets can now enjoy\u200b a longer, happier life.<\/p>\n<p>Moreover,\u2063 this drug\u2064 could \u2063also \u2064encourage more adoption of bigger dogs from shelters \u200band rescues. Many people are reluctant to adopt larger breeds due to the potential challenges associated with their shorter lifespans. With the availability of a drug that can extend their lifespan, more people\u200c may be inclined to give these dogs a loving\u200d home.<\/p>\n<p>However, it is important to note that the drug is \u2063still in\u2063 the approval process. While the FDA has granted conditional approval for its use in large dog \u200clifespan extension, further studies \u200cand testing are \u200brequired to \u200bensure its effectiveness and safety in the long term.<\/p>\n<\/blockquote>\n<h3>Conclusion<\/h3>\n<blockquote>\n<p>The \u2062development of a groundbreaking drug that could extend the lifespan of big dogs is certainly exciting news for dog owners and enthusiasts. If \u2064approved, this drug has the potential to address\u2062 one of the biggest flaws associated with \u200bowning \u200clarger breeds and could significantly \u2064improve their overall well-being.<\/p>\n<p>While more research and testing are needed, the promising results so far provide hope that this drug could soon become a \u2064game-changer in the canine world. It \u2064not only offers the possibility\u200c of longer and healthier lives for big dogs but also opens doors for the adoption of these wonderful animals by more\u200d people.<\/p>\n<p>Indeed, this breakthrough\u2062 drug could \u2063be the key to ensuring that big dogs get to\u200d enjoy the fullest and longest lives possible, bringing joy and companionship to their owners for many years to \u200ccome.<\/p>\n<\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>A larger breed dog is the higher cost of care, including food, grooming, and veterinary expenses. They also require more space and exercise. Additionally, larger dogs may have shorter lifespans and are prone to certain health issues. Despite these drawbacks, many still find the rewards of owning a big dog outweigh the challenges<\/p>\n","protected":false},"author":2015,"featured_media":2121153,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mo_disable_npp":"","fifu_image_url":"https:\/\/cndimages.nyc3.digitaloceanspaces.com\/breaking-news\/wp-content\/uploads\/2021\/01\/IMG_2758-scaled-1.jpg","fifu_image_alt":"","footnotes":""},"categories":[548],"tags":[],"class_list":["post-2121152","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-conservative-news-daily"],"fifu_image_url":"https:\/\/cndimages.nyc3.digitaloceanspaces.com\/breaking-news\/wp-content\/uploads\/2021\/01\/IMG_2758-scaled-1.jpg","_links":{"self":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2121152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/users\/2015"}],"replies":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/comments?post=2121152"}],"version-history":[{"count":0,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/2121152\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media\/2121153"}],"wp:attachment":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media?parent=2121152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/categories?post=2121152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/tags?post=2121152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}