{"id":1927791,"date":"2023-05-10T02:12:12","date_gmt":"2023-05-10T06:12:12","guid":{"rendered":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/microorganisms-in-the-gut-decide-how-well-your-body-fights-cancer\/"},"modified":"2023-05-10T02:19:44","modified_gmt":"2023-05-10T06:19:44","slug":"microorganisms-in-the-gut-decide-how-well-your-body-fights-cancer","status":"publish","type":"post","link":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/microorganisms-in-the-gut-decide-how-well-your-body-fights-cancer\/","title":{"rendered":"Gut Microbes Affect Cancer Defense."},"content":{"rendered":"<aside class=\"mashsb-container mashsb-main mashsb-stretched\"><div class=\"mashsb-box\"><div class=\"mashsb-count mash-medium\" style=\"&quot;\"><div class=\"counts mashsbcount\">10<\/div><span class=\"mashsb-sharetext\">SHARES<\/span><\/div><div class=\"mashsb-buttons\"><a class=\"mashicon-facebook mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fwww.conservativenewsdaily.net%2Fbreaking-news%2Fmicroorganisms-in-the-gut-decide-how-well-your-body-fights-cancer%2F\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Facebook<\/span><\/a><a class=\"mashicon-twitter mash-medium mash-nomargin mashsb-noshadow\" href=\"https:\/\/twitter.com\/intent\/tweet?text=&amp;url=https:\/\/www.conservativenewsdaily.net\/breaking-news\/?p=1927791&amp;via=ConservNewsDly\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Twitter<\/span><\/a><a class=\"mashicon-subscribe mash-medium mash-nomargin mashsb-noshadow\" href=\"#\" target=\"_top\" rel=\"nofollow\"><span class=\"icon\"><\/span><span class=\"text\">Subscribe<\/span><\/a><div class=\"onoffswitch2 mash-medium mashsb-noshadow\" style=\"display:none\"><\/div><\/div>\n            <\/div>\n                <div style=\"clear:both\"><\/div><\/aside>\n            <!-- Share buttons by mashshare.net - Version: 4.0.47--><h2>The Miraculous Qualities of Gut Microbes in Fighting Disease<\/h2>\n<p>In this series, we\u2019ll share how the latest developments in this medical frontier are transforming our approaches to illness and offering new strategies to heal and prevent disease.<\/p>\n<h3>The Hype Around Gut Microbial Health<\/h3>\n<p>Mind-blowing studies are revealing miraculous qualities of our gut microbes, including their ability to mediate prolific killers such as cancer and heart disease. This collection of bacteria, viruses, and fungi that make up about 70 percent of our immune system has become a huge topic for researchers and authors. Hope is the latest theme in many books. It comes as research reveals gut damage from antibiotics, glyphosate, sugar, and stress can be reversed and our gut microbiome can recover. A wave of revelations over the past two decades has fed a new enthusiasm: If you nurture the bugs in your gut, they can do the work of preventing and even fighting diseases for you.<\/p>\n<p>The hype that gut microbial health is human health is here to stay, according to Dr. William Li, a world-renowned physician and author. His latest book, \u201cEat to Beat Your Diet\u201d focuses on metabolism, the major role of our gut microbes.<\/p>\n<p><strong>\u201cYou can see that the health of our gut bacteria has profound importance for our overall health,\u201d<\/strong> Li told The Epoch Times. <strong>\u201cThese bacteria live in harmony with one another in which most of these bacteria are there for profound functions.\u201d<\/strong><\/p>\n<p>One specific bacteria Li likes to highlight is Akkermansia muciniphila (A. muciniphila), which plays a role in metabolism, body weight, immune defenses, and mental well-being. It\u2019s often found in the guts of lean people and absent in those who are obese.<\/p>\n<h3>Miracle Cancer Bug?<\/h3>\n<p>Akkermansia was identified in 2015 research as a key healthy gut bacteria that predicts a better response to cancer immunotherapy, a type of treatment that leverages patients\u2019 own immune systems in fighting the disease.<\/p>\n<p>The study, published in Science, sought to determine why only about 20 percent of patients had tremendous success with <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/fda-slows-approval-of-affordable-cancer-drug-in-the-name-of-racial-equity\/\" title=\"FDA Slows Approval Of Affordable Cancer Drug In The Name Of Racial \u2018Equity\u2019\">immune checkpoint inhibitors<\/a>, a type of drug that signals the immune system at a cellular level. While less harsh than chemotherapy, it still has <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/fact-check-image-claims-a-new-study-found-ivermectin-causes-sterility-in-85-of-men\/\" title=\"FACT CHECK: Image Claims A \u2018New\u2019 Study Found Ivermectin Causes Sterility In 85% Of Men\">common side effects<\/a> of rash, diarrhea, and fatigue. Stool samples from patients with lung and kidney cancers showed those not responding to immunotherapy had low levels of A. muciniphila. That ignited research into the microbiome\u2019s role in cancer.<\/p>\n<p><strong>\u201cWith a good activated immune system, you\u2019re able to take stage 3 or stage 4 cancer and reverse it to zero,\u201d<\/strong> Li said. <strong>\u201cSome of the most eye-opening research in the last five years has been in the studies of cancer patients, certain bacteria present in the gut of those responding to this powerful treatment.<\/strong><\/p>\n<p><strong>\u201cThat makes gut health a matter of life and death.\u201d<\/strong><\/p>\n<h3>Bugs Protecting Your Heart<\/h3>\n<p>Though the mechanisms are a bit complex, there is loads of evidence that metabolism in the microbiome leads to the regulation of blood pressure, cholesterol, vascular inflammation, atherosclerosis, and calcium buildup in the arteries.<\/p>\n<p><strong>\u201cNew therapeutic approaches that target gut microbes for the treatment and prevention of CVDs [cardiovascular diseases] represent exciting areas of investigation,\u201d<\/strong> notes a 2020 research review in Circulation Research that links six pathways from the gut to heart disease. <strong>\u201cAlthough our knowledge about how microbiota impact CVD is still rudimentary, the rate at which new discoveries are emerging is impressive.\u201d<\/strong><\/p>\n<p>That same bug that plays a big role in immunotherapy, A. muciniphila, also seems to be key in reducing risks associated with heart disease, according to the research. It appears to reduce aortic atherosclerosis, a <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/an-autopsy-report-on-dead-bodybuilders\/\" title=\"An Autopsy Report on Dead Bodybuilders\">cardiovascular disease risk factor<\/a>, and is being investigated as a therapeutic in human studies. In one trial against a placebo, it was found to reduce plasma lipopolysaccharide in people who were obese and had metabolic syndrome.<\/p>\n<p>Lipopolysaccharides (LPS) are large molecules made of fat and polycarbohydrates that are found on half or more of the intestinal bacteria, encasing and protecting them from being digested by bile salts. But when LPS escapes the colon and crosses into the bloodstream, it becomes an endotoxin\u2013bringing with it a storm of inflammation. LPS is a biomarker for infection in the body, and it\u2019s used in animal studies to create an inflammatory response.<\/p>\n<p>LPS is associated with heart disease and Alzheimer\u2019s disease. There\u2019s evidence published in the 2008 Journal of Neuroimmunology that blood plasma in Alzheimer\u2019s patients has three times the LPS as healthy controls.<\/p>\n<h3>The Vitamin D Connection<\/h3>\n<p>The microbiome is largely manipulated through diet, but food is a poor source of vitamin D, which really acts more like a hormone than a vitamin in the body. There is no vitamin D receptor in the gut; however, new research is pointing to vitamin D\u2019s role in microbiome health.<\/p>\n<p>Vitamin D is naturally produced when the skin (minus sunscreen) is exposed to sunlight, especially around midday. Amid our modern indoor lifestyle, it\u2019s more reliably increased with supplementation. It\u2019s well-known that vitamin D decreases inflammation. Another key anti-inflammatory mechanism comes from <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/taking-resveratrol-to-control-fat-metabolism\/\" title=\"Taking Resveratrol to Control Fat Metabolism\">short-chain fatty acids<\/a> (SCFA), the metabolites that are made when microbes feast on fiber in the colon. SCFAs put out inflammatory fires all over the body.<\/p>\n<p>Leigh A. Frame, associate director of the George Washington University Resiliency &#038; Well-being Center, told doctors at the Malibu Microbiome Meeting that SCFAs enhance the ability of vitamin D to promote antimicrobial peptides, which are secreted by immune and epithelial cells for intestinal barrier defense. These powerful peptides bind LPS and modulate the expression of cytokines, playing an anti-inflammatory role in disease, infection, and cancer.<\/p>\n<p><strong>\u201cOne thing we do know is <a href=\"https:\/\/www.conservativenewsdaily.net\/breaking-news\/microorganisms-in-the-gut-decide-how-well-your-body-fights-cancer\/\" title=\"Gut Microbes Affect Cancer Defense.\">short-chain fatty acids enhance vitamin<\/a> D to build the gut barrier,\u201d<\/strong> Frame, a nutrition and microbiome expert, said.<\/p>\n<p>A 2020 article in a Japanese medical journal concluded that vitamin D controls antimicrobial peptide expression, as well as modulating intestinal microbiome function, and having a protective effect on the epithelial barriers in the gut mucosa.<\/p>\n<p>Another study in a 2021 special International Journal of Molecular Sciences reported that vitamin D supplementation was responsible for reducing inflammation in people with inflammatory bowel disease (IBD), as well as improving the makeup of the microbiota.<\/p>\n<h3>Gut Diseases and Disruptions<\/h3>\n<p>Gut diseases such as IBD are illnesses of Western civilization\u2014not a function of genetics but a function of a lifestyle marked by chemical exposures and disruptions to the gut barrier, according to Dr. Ari Grinspan, associate professor of medicine and director of the fecal microbiota transplant program at Mount Sinai Hospital.<\/p>\n<p>He told The Epoch Times that there\u2019s promise on the horizon that changing the makeup of the microbiota can have a significant impact on serious diseases.<\/p>\n<p><strong>\u201cThere\u2019s so much potential. We have to be cautiously optimistic. A lot of these things are not going to pan out,\u201d<\/strong> he said. <strong>\u201cBut maybe there will be a subset of these patients that we can help by using alterations in the microbiome. That\u2019s why I\u2019m very excited about where this leads us in the future.\u201d<\/strong><\/p>\n<h3>How to Know if You Are at Risk for Microbiome-Related Diseases<\/h3>\n<p>How do you know if you are at risk for microbiome-related diseases? It\u2019s not always obvious, but a personal inventory of toxins, body mass, and sleep offer clues.<\/p>\n<p>Read Part 1 \u2013 Killing Bacteria with Antimicrobials and Antibiotics May Be Shortsighted, According to New Science About the Microbiome<\/p>\n<p>Read Part 2 \u2013 How the Gut Cures and Creates Disease<\/p>\n<p>Read Part 3 \u2013 Why Scientists Are Obsessing Over the Bugs in Our Stool<\/p>\n<p>Read Part 4 \u2013 Decoding Dysbiosis: Are Your Gut Microbes Out of Whack?<\/p>\n<p>Read Part 5 \u2013 Our Gut Bugs Make Tiny Metabolites That Have Gigantic Jobs<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this series, we\u2019ll share how the latest developments in this medical frontier are transforming our approaches to illness and offering new strategies to heal and prevent disease. Previously: Short-chain fatty acids\u2014created by the microbiome\u2014are the main metabolites it makes that link the gut to disease.\u00a0 Mind-blowing studies are revealing miraculous qualities of our gut<\/p>\n","protected":false},"author":1,"featured_media":1927792,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mo_disable_npp":"","fifu_image_url":"https:\/\/cndimages.nyc3.digitaloceanspaces.com\/breaking-news\/wp-content\/uploads\/2021\/01\/IMG_2758-scaled-1.jpg","fifu_image_alt":"","footnotes":""},"categories":[547],"tags":[7622,8047,3998,12923,14529],"class_list":["post-1927791","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-the-bongino-report","tag-affect","tag-cancer","tag-defense","tag-gut","tag-microbes"],"fifu_image_url":"https:\/\/cndimages.nyc3.digitaloceanspaces.com\/breaking-news\/wp-content\/uploads\/2021\/01\/IMG_2758-scaled-1.jpg","_links":{"self":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/1927791","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/comments?post=1927791"}],"version-history":[{"count":0,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/posts\/1927791\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media\/1927792"}],"wp:attachment":[{"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/media?parent=1927791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/categories?post=1927791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.conservativenewsdaily.net\/breaking-news\/wp-json\/wp\/v2\/tags?post=1927791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}